Assay Detail
Functional
CHEMBL4124573
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Antiproliferative activity against human MG63 cells after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MG-63 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Computer-aided discovery and biological characterization of human lactate dehydrogenase 5 inhibitors with anti-osteosarcoma activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.84 | 6.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4065858 | — | — | 1 | 6.18 |
| CHEMBL4126746 | — | — | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4065858 | — | IC50 | = | 660.0 | nM | 6.18 |
| CHEMBL4126746 | — | IC50 | = | 3180.0 | nM | 5.50 |