Assay Detail
Binding
CHEMBL4124811
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Agonist activity at monkey glucagon receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Macaca mulatta |
| Cell Type | HEK293 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 9.89 | 9.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4126738 | — | — | 1 | 9.89 |
| CHEMBL5314341 | GLUCAGON | 4.0 | 1 | - |
| CHEMBL4128276 | — | — | 1 | - |
| CHEMBL4524066 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4126738 | — | EC50 | = | 0.129 | nM | 9.89 |
| CHEMBL5314341 | GLUCAGON | EC50 | = | 0.0015 | nM | - |
| CHEMBL4128276 | — | EC50 | > | 1.0 | 10'8pM | - |
| CHEMBL4524066 | — | EC50 | > | 1.0 | 10'8pM | - |