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Assay Detail

CHEMBL4125401

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Functional
Antioxidant activity assessed as DPPH radical scavenging activity measured after 30 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Synthesis of coumarin derivatives and their cytoprotective effects on t-BHP-induced oxidative damage in HepG2 cells.
Ando T, Nagumo M, Ninomiya M, Tanaka K, Linhardt RJ, Koketsu M.
Bioorg Med Chem Lett (2018) 28 : 2422 -2425
PubMed 29914769 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 3 6.03 6.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL50 QUERCETIN 3.0 1 6.77
CHEMBL17001 METHYLCAFFEATE 1 5.82
CHEMBL4128730 1 5.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL50 QUERCETIN EC50 = 170.0 nM 6.77
CHEMBL17001 METHYLCAFFEATE EC50 = 1500.0 nM 5.82
CHEMBL4128730 EC50 = 3060.0 nM 5.51