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Assay Detail

CHEMBL4125434

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of recombinant human MAO-A expressed in baculovirus infected insect cells using aminoproplyether of luciferin methyl ester as substrate after 90 mins by chemiluminescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Amine oxidase [flavin-containing] A (CHEMBL1951)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Selective inhibition of monoamine oxidase A by chelerythrine, an isoquinoline alkaloid.
Baek SC, Ryu HW, Kang MG, Lee H, Park D, Cho ML, Oh SR, Kim H.
Bioorg Med Chem Lett (2018) 28 : 2403 -2407
PubMed 29925480 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.66 4.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL592005 MALVIDIN CHLORIDE 1 4.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL592005 MALVIDIN CHLORIDE IC50 = 22100.0 nM 4.66