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Assay Detail

CHEMBL4130645

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against wild type mouse Hepa1c1c7 cells after 48 hrs by SRB assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Medchemcomm (2016) 7 : 2395 -2409
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 4.26 4.48

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL487051 1 4.48
CHEMBL4170149 1 4.41
CHEMBL510834 1 4.07
CHEMBL294099 1 4.07
CHEMBL242080 E319 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL487051 IC50 = 33000.0 nM 4.48
CHEMBL4170149 IC50 = 39000.0 nM 4.41
CHEMBL510834 IC50 = 85000.0 nM 4.07
CHEMBL294099 IC50 = 85000.0 nM 4.07
CHEMBL242080 E319 IC50 = 147000.0 nM -