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Assay Detail

CHEMBL4130657

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human TK10 cells assessed as cell survival after 24 hrs by SRB assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type TK-10
Confidence 1 — Organism
Curated By Intermediate

Target

TK-10 (CHEMBL614056)
Type CELL-LINE
Organism Homo sapiens

Publication

Medchemcomm (2016) 7 : 2395 -2409
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 4.72 4.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL487051 1 4.85
CHEMBL4165686 1 4.75
CHEMBL4166894 1 4.70
CHEMBL4162238 1 4.70
CHEMBL4170149 1 4.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL487051 IC50 = 14000.0 nM 4.85
CHEMBL4165686 IC50 = 18000.0 nM 4.75
CHEMBL4166894 IC50 = 20000.0 nM 4.70
CHEMBL4162238 IC50 = 20000.0 nM 4.70
CHEMBL4170149 IC50 = 26000.0 nM 4.58