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Assay Detail

CHEMBL4132087

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibition of human MCF7/ADR cells after 72 hrs by MTT assay
4
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NCI/ADR-RES
Confidence 1 — Organism
Curated By Intermediate

Target

NCI/ADR-RES (CHEMBL613829)
Type CELL-LINE
Organism Homo sapiens

Publication

Click chemistry-based synthesis and anticancer activity evaluation of novel C-14 1,2,3-triazole dehydroabietic acid hybrids.
Hou W, Luo Z, Zhang G, Cao D, Li D, Ruan H, Ruan BH, Su L, Xu H.
Eur J Med Chem (2017) 138 : 1042 -1052
PubMed 28759877 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
GI 3 - -
IC50 1 6.05 6.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4160194 2 6.05
CHEMBL4168053 1 -
CHEMBL4160131 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4160194 IC50 = 900.0 nM 6.05
CHEMBL4168053 GI - -
CHEMBL4160131 GI - -
CHEMBL4160194 GI - -