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Assay Detail

CHEMBL4133601

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as redox reaction between compound and MTT in DMSO measured after 6 hrs
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Lipid Peroxidation and Cyclooxygenase Enzyme Inhibitory Compounds from Prangos haussknechtii.
Dissanayake AA, Ameen BAH, Nair MG.
J Nat Prod (2017) 80 : 2472 -2477
PubMed 28885836 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 4.24 4.31

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4166924 1 4.31
CHEMBL4159700 1 4.17
CHEMBL4173681 1 -
CHEMBL4170326 1 -
CHEMBL196 ASCORBIC ACID 4.0 1 -
CHEMBL242080 E319 1 -
CHEMBL146 BUTYLATED HYDROXYTOLUENE 2.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4166924 IC50 = 48600.0 nM 4.31
CHEMBL4159700 IC50 = 67100.0 nM 4.17
CHEMBL4173681 IC50 = 121900.0 nM -
CHEMBL4170326 IC50 = 128200.0 nM -
CHEMBL196 ASCORBIC ACID IC50 = 142100.0 nM -
CHEMBL242080 E319 IC50 = 150400.0 nM -
CHEMBL146 BUTYLATED HYDROXYTOLUENE IC50 - -