Assay Detail
Functional
CHEMBL4133602
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Antioxidant activity assessed as inhibition of ferrous chloride-induced lipid peroxidation in DHA-PA labelled SLPC large unilamellar vesicle measured over 21 mins by fluorescence assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Lipid Peroxidation and Cyclooxygenase Enzyme Inhibitory Compounds from Prangos haussknechtii.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 4.39 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL146 | BUTYLATED HYDROXYTOLUENE | 2.0 | 1 | 5.16 |
| CHEMBL242080 | E319 | — | 1 | 5.00 |
| CHEMBL4166924 | — | — | 1 | 4.37 |
| CHEMBL4173681 | — | — | 1 | 4.20 |
| CHEMBL448060 | ISOIMPERATORIN | — | 1 | 4.20 |
| CHEMBL510120 | OXYPEUCEDANIN | — | 1 | 4.13 |
| CHEMBL4170326 | — | — | 1 | 4.07 |
| CHEMBL1455497 | MALIC ACID | 2.0 | 1 | 4.01 |
| CHEMBL4159700 | — | — | 1 | - |
| CHEMBL196 | ASCORBIC ACID | 4.0 | 1 | - |
| CHEMBL52229 | OSTHOLE | — | 1 | - |
| CHEMBL1778420 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL146 | BUTYLATED HYDROXYTOLUENE | IC50 | = | 6900.0 | nM | 5.16 |
| CHEMBL242080 | E319 | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL4166924 | — | IC50 | = | 43000.0 | nM | 4.37 |
| CHEMBL4173681 | — | IC50 | = | 62600.0 | nM | 4.20 |
| CHEMBL448060 | ISOIMPERATORIN | IC50 | = | 63700.0 | nM | 4.20 |
| CHEMBL510120 | OXYPEUCEDANIN | IC50 | = | 74800.0 | nM | 4.13 |
| CHEMBL4170326 | — | IC50 | = | 86100.0 | nM | 4.07 |
| CHEMBL1455497 | MALIC ACID | IC50 | = | 97700.0 | nM | 4.01 |
| CHEMBL4159700 | — | IC50 | = | 113900.0 | nM | - |
| CHEMBL196 | ASCORBIC ACID | IC50 | - | — | - | |
| CHEMBL52229 | OSTHOLE | IC50 | = | 119700.0 | nM | - |
| CHEMBL1778420 | — | IC50 | = | 161400.0 | nM | - |