Assay Detail
Binding
CHEMBL4134317
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at dog CCR4
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Canis lupus familiaris |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Target
C-C chemokine receptor type 4 (CHEMBL4295899) ↗| Type | SINGLE PROTEIN |
| Organism | Canis lupus familiaris |
Publication
Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.05 | 8.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4172635 | — | — | 1 | 8.50 |
| CHEMBL4169247 | — | — | 1 | 7.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4172635 | — | IC50 | = | 3.162 | nM | 8.50 |
| CHEMBL4169247 | — | IC50 | = | 25.12 | nM | 7.60 |