Assay Detail
Functional
CHEMBL4135167
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Antiproliferative activity against human MV4-11 cells after 10 days by MTS assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MV4-11 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.79 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3906257 | — | — | 1 | 7.52 |
| CHEMBL4176756 | — | — | 1 | 6.70 |
| CHEMBL4170367 | — | — | 1 | 6.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3906257 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL4176756 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL4170367 | — | IC50 | = | 700.0 | nM | 6.16 |