Assay Detail
Functional
CHEMBL4135404
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antioxidant activity assessed as H2O2 free radical scavenging activity after 1 hr by UV spectrophotometric analysis
15
Total Activities
13
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Therapeutic investigations of novel indoxyl-based indolines: A drug target validation and Structure-Activity Relationship of angiotensin-converting enzyme inhibitors with cardiovascular regulation and thrombolytic potential.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 12 | - | - |
| IC50 | 3 | 8.35 | 8.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4174467 | — | — | 2 | 8.60 |
| CHEMBL4160421 | — | — | 2 | 8.37 |
| CHEMBL196 | ASCORBIC ACID | 4.0 | 1 | 8.08 |
| CHEMBL4163389 | — | — | 1 | - |
| CHEMBL4171024 | — | — | 1 | - |
| CHEMBL4167651 | — | — | 1 | - |
| CHEMBL4175518 | — | — | 1 | - |
| CHEMBL4159339 | — | — | 1 | - |
| CHEMBL4167252 | — | — | 1 | - |
| CHEMBL4163798 | — | — | 1 | - |
| CHEMBL4166152 | — | — | 1 | - |
| CHEMBL4174072 | — | — | 1 | - |
| CHEMBL4163792 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4174467 | — | IC50 | = | 2.5 | nM | 8.60 |
| CHEMBL4160421 | — | IC50 | = | 4.25 | nM | 8.37 |
| CHEMBL196 | ASCORBIC ACID | IC50 | = | 8.25 | nM | 8.08 |
| CHEMBL4163389 | — | Activity | - | — | - | |
| CHEMBL4171024 | — | Activity | - | — | - | |
| CHEMBL4160421 | — | Activity | - | — | - | |
| CHEMBL4167651 | — | Activity | - | — | - | |
| CHEMBL4175518 | — | Activity | - | — | - | |
| CHEMBL4159339 | — | Activity | - | — | - | |
| CHEMBL4167252 | — | Activity | - | — | - | |
| CHEMBL4174467 | — | Activity | - | — | - | |
| CHEMBL4163798 | — | Activity | - | — | - | |
| CHEMBL4166152 | — | Activity | - | — | - | |
| CHEMBL4174072 | — | Activity | - | — | - | |
| CHEMBL4163792 | — | Activity | - | — | - |