Assay Detail
Functional
CHEMBL4136413
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Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect incubated for 48 hrs by Cell-titer-Glo assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus |
| Cell Type | MDCK |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Structure Optimization of Aloperine Derivatives as HIV-1 Entry Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 4.78 | 4.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3329704 | — | — | 1 | 4.84 |
| CHEMBL3804997 | — | — | 1 | 4.72 |
| CHEMBL4166312 | — | — | 1 | - |
| CHEMBL4173026 | — | — | 1 | - |
| CHEMBL4160685 | — | — | 1 | - |
| CHEMBL4176960 | — | — | 1 | - |
| CHEMBL4170142 | — | — | 1 | - |
| CHEMBL4159520 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3329704 | — | EC50 | = | 14500.0 | nM | 4.84 |
| CHEMBL3804997 | — | EC50 | = | 18900.0 | nM | 4.72 |
| CHEMBL4166312 | — | EC50 | - | — | - | |
| CHEMBL4173026 | — | EC50 | - | — | - | |
| CHEMBL4160685 | — | EC50 | - | — | - | |
| CHEMBL4176960 | — | EC50 | - | — | - | |
| CHEMBL4170142 | — | EC50 | - | — | - | |
| CHEMBL4159520 | — | EC50 | - | — | - |