Assay Detail
Functional
CHEMBL4138684
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity in human Lu1 cells assessed as reduction in cell growth incubated for 72 hrs by neutral red staining based colorimetry
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Lu1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis and cytotoxicity of bengamide analogues and their epimers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.19 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4159587 | — | — | 1 | 6.30 |
| CHEMBL123 | ELLIPTECINE | — | 1 | 5.80 |
| CHEMBL4165136 | — | — | 1 | 5.37 |
| CHEMBL4170216 | — | — | 1 | 5.00 |
| CHEMBL4164455 | — | — | 1 | 4.76 |
| CHEMBL1236230 | — | — | 1 | 4.63 |
| CHEMBL4166377 | — | — | 1 | 4.44 |
| CHEMBL4174616 | — | — | 1 | - |
| CHEMBL4168335 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4159587 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL123 | ELLIPTECINE | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL4165136 | — | IC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL4170216 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL4164455 | — | IC50 | = | 17200.0 | nM | 4.76 |
| CHEMBL1236230 | — | IC50 | = | 23400.0 | nM | 4.63 |
| CHEMBL4166377 | — | IC50 | = | 36300.0 | nM | 4.44 |
| CHEMBL4174616 | — | IC50 | > | 150000.0 | nM | - |
| CHEMBL4168335 | — | IC50 | > | 150000.0 | nM | - |