Assay Detail
Functional
CHEMBL4138686
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Cytotoxicity in human MCF7 cells assessed as reduction in cell growth incubated for 72 hrs by neutral red staining based colorimetry
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis and cytotoxicity of bengamide analogues and their epimers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.39 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4159587 | — | — | 1 | 6.70 |
| CHEMBL4165136 | — | — | 1 | 5.89 |
| CHEMBL123 | ELLIPTECINE | — | 1 | 5.62 |
| CHEMBL1236230 | — | — | 1 | 4.63 |
| CHEMBL4166377 | — | — | 1 | 4.09 |
| CHEMBL4170216 | — | — | 1 | - |
| CHEMBL4164455 | — | — | 1 | - |
| CHEMBL4174616 | — | — | 1 | - |
| CHEMBL4168335 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4159587 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL4165136 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL123 | ELLIPTECINE | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL1236230 | — | IC50 | = | 23400.0 | nM | 4.63 |
| CHEMBL4166377 | — | IC50 | = | 80400.0 | nM | 4.09 |
| CHEMBL4170216 | — | IC50 | = | 144500.0 | nM | - |
| CHEMBL4164455 | — | IC50 | = | 164900.0 | nM | - |
| CHEMBL4174616 | — | IC50 | > | 150000.0 | nM | - |
| CHEMBL4168335 | — | IC50 | > | 150000.0 | nM | - |