Assay Detail
Functional
CHEMBL4138688
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Cytotoxicity in human HeLa cells assessed as reduction in cell growth incubated for 72 hrs by neutral red staining based colorimetry
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis and cytotoxicity of bengamide analogues and their epimers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.13 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL123 | ELLIPTECINE | — | 1 | 5.80 |
| CHEMBL4159587 | — | — | 1 | 5.68 |
| CHEMBL4164455 | — | — | 1 | 4.81 |
| CHEMBL4165136 | — | — | 1 | 4.22 |
| CHEMBL4170216 | — | — | 1 | - |
| CHEMBL1236230 | — | — | 1 | - |
| CHEMBL4166377 | — | — | 1 | - |
| CHEMBL4174616 | — | — | 1 | - |
| CHEMBL4168335 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL123 | ELLIPTECINE | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL4159587 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL4164455 | — | IC50 | = | 15400.0 | nM | 4.81 |
| CHEMBL4165136 | — | IC50 | = | 60700.0 | nM | 4.22 |
| CHEMBL4170216 | — | IC50 | > | 150000.0 | nM | - |
| CHEMBL1236230 | — | IC50 | > | 150000.0 | nM | - |
| CHEMBL4166377 | — | IC50 | > | 150000.0 | nM | - |
| CHEMBL4174616 | — | IC50 | > | 150000.0 | nM | - |
| CHEMBL4168335 | — | IC50 | > | 150000.0 | nM | - |