Assay Detail
Binding
CHEMBL4138817
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant HQ5-Halo-tagged JARID1A PHD3 finger domain (unknown origin) expressed in BL21(DE3)pLysS cells after 1 hr by chemiluminescent assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Methyllysine binding domains: Structural insight and small molecule probe development.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.58 | 4.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4129540 | — | — | 1 | 4.58 |
| CHEMBL4126240 | — | — | 1 | 4.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4129540 | — | IC50 | = | 26000.0 | nM | 4.58 |
| CHEMBL4126240 | — | IC50 | = | 26000.0 | nM | 4.58 |