Assay Detail
Functional
CHEMBL4138874
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Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New cycloartane type-triterpenoids from the areal parts of Caragana sukiensis and their biological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 4.85 | 5.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.95 |
| CHEMBL4171632 | — | — | 1 | 5.75 |
| CHEMBL1762007 | SOYASAPOGENOL B | — | 1 | 5.63 |
| CHEMBL4175075 | — | — | 1 | 5.53 |
| CHEMBL4159948 | — | — | 1 | 4.61 |
| CHEMBL4167864 | — | — | 1 | 4.57 |
| CHEMBL4161026 | — | — | 1 | 4.54 |
| CHEMBL4170605 | — | — | 1 | 4.54 |
| CHEMBL500607 | — | — | 1 | 4.51 |
| CHEMBL455098 | beta-AMYRIN | — | 1 | 4.45 |
| CHEMBL4171223 | — | — | 1 | 4.41 |
| CHEMBL4163320 | — | — | 1 | 4.37 |
| CHEMBL4161461 | — | — | 1 | 4.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 1117.0 | nM | 5.95 |
| CHEMBL4171632 | — | IC50 | = | 1778.0 | nM | 5.75 |
| CHEMBL1762007 | SOYASAPOGENOL B | IC50 | = | 2328.0 | nM | 5.63 |
| CHEMBL4175075 | — | IC50 | = | 2931.0 | nM | 5.53 |
| CHEMBL4159948 | — | IC50 | = | 24810.0 | nM | 4.61 |
| CHEMBL4167864 | — | IC50 | = | 27160.0 | nM | 4.57 |
| CHEMBL4161026 | — | IC50 | = | 28820.0 | nM | 4.54 |
| CHEMBL4170605 | — | IC50 | = | 28650.0 | nM | 4.54 |
| CHEMBL500607 | — | IC50 | = | 31180.0 | nM | 4.51 |
| CHEMBL455098 | beta-AMYRIN | IC50 | = | 35310.0 | nM | 4.45 |
| CHEMBL4171223 | — | IC50 | = | 38850.0 | nM | 4.41 |
| CHEMBL4163320 | — | IC50 | = | 43170.0 | nM | 4.37 |
| CHEMBL4161461 | — | IC50 | = | 58220.0 | nM | 4.24 |