Assay Detail
Functional
CHEMBL4139854
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against CSFV infected in SK6 cells assessed as reduction of pseudo-plaque formation after 2 days by immunoperoxidase monolayer assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Classical swine fever virus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Classical swine fever virus (CHEMBL4296565) ↗| Type | ORGANISM |
| Organism | Classical swine fever virus |
Publication
Novel thioglycosyl analogs of glycosyltransferase substrates as antiviral compounds against classical swine fever virus and hepatitis C virus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 4.79 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4173159 | — | — | 1 | 5.52 |
| CHEMBL4162474 | — | — | 1 | 5.22 |
| CHEMBL4174229 | — | — | 1 | 4.89 |
| CHEMBL4166328 | — | — | 1 | 4.31 |
| CHEMBL4169743 | — | — | 1 | 4.01 |
| CHEMBL4176671 | — | — | 1 | - |
| CHEMBL4162872 | — | — | 1 | - |
| CHEMBL4170810 | — | — | 1 | - |
| CHEMBL4159085 | — | — | 1 | - |
| CHEMBL4171182 | — | — | 1 | - |
| CHEMBL1259059 | SOFOSBUVIR | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4173159 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL4162474 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL4174229 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL4166328 | — | IC50 | = | 49000.0 | nM | 4.31 |
| CHEMBL4169743 | — | IC50 | = | 97000.0 | nM | 4.01 |
| CHEMBL4176671 | — | IC50 | = | 103000.0 | nM | - |
| CHEMBL4162872 | — | IC50 | > | 325000.0 | nM | - |
| CHEMBL4170810 | — | IC50 | > | 299000.0 | nM | - |
| CHEMBL4159085 | — | IC50 | = | 320000.0 | nM | - |
| CHEMBL4171182 | — | IC50 | = | 370000.0 | nM | - |
| CHEMBL1259059 | SOFOSBUVIR | IC50 | - | — | - |