Assay Detail
Functional
CHEMBL4141904
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Cytotoxicity against human A549 cells after 48 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Cytotoxicity, Hemolytic Toxicity, and Mechanism of Action of Pulsatilla Saponin D and Its Synthetic Derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.22 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL479310 | HEDERACOLCHISIDE A | — | 1 | 5.22 |
| CHEMBL4169729 | — | — | 1 | - |
| CHEMBL4160569 | — | — | 1 | - |
| CHEMBL4171167 | — | — | 1 | - |
| CHEMBL4162587 | — | — | 1 | - |
| CHEMBL4170516 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL479310 | HEDERACOLCHISIDE A | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL4169729 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4160569 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4171167 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4162587 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4170516 | — | IC50 | > | 10000.0 | nM | - |