Assay Detail
Binding
CHEMBL4144358
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Inhibition of HDAC2 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Dual NAMPT/HDAC Inhibitors as a New Strategy for Multitargeting Antitumor Drug Discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.68 | 8.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4170617 | — | — | 1 | 8.17 |
| CHEMBL4163681 | — | — | 1 | 7.48 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4170617 | — | IC50 | = | 6.8 | nM | 8.17 |
| CHEMBL4163681 | — | IC50 | = | 33.0 | nM | 7.48 |
| CHEMBL98 | VORINOSTAT | IC50 | = | 40.0 | nM | 7.40 |