Assay Detail
Binding
CHEMBL4144602
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human neutrophil elastase using N-Methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilid as substrate measured after 1 hr
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Probing the Antiallergic and Anti-inflammatory Activity of Biflavonoids and Dihydroflavonols from Dietes bicolor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.89 | 5.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL63354 | AMENTOFLAVONE | — | 1 | 5.90 |
| CHEMBL63677 | ROBUSTAFLAVONE | — | 1 | 5.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL63354 | AMENTOFLAVONE | IC50 | = | 1270.0 | nM | 5.90 |
| CHEMBL63677 | ROBUSTAFLAVONE | IC50 | = | 1330.0 | nM | 5.88 |