Assay Detail
ADMET
CHEMBL4144853
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Inhibition of CYP2C8 (unknown origin)
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis of Novel Tetrahydroisoquinoline CXCR4 Antagonists with Rigidified Side-Chains.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.07 | 5.39 |
| Inhibition | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4167221 | — | — | 1 | 5.39 |
| CHEMBL4169450 | — | — | 1 | 4.75 |
| CHEMBL4086147 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4167221 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL4169450 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL4086147 | — | Inhibition | - | % | - |