Assay Detail
Functional
CHEMBL4145170
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at N-terminal FLAG-tagged human CB1 receptor transfected in human HTLA cells assessed as induction of beta-arrestin-recruitment after 8 to 14 hrs by bright-glo luminescence based assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Antitumorigenic Properties of Omega-3 Endocannabinoid Epoxides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 9.76 | 10.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4169198 | — | — | 1 | 10.52 |
| CHEMBL4177060 | — | — | 1 | 10.15 |
| CHEMBL4172580 | — | — | 1 | 9.72 |
| CHEMBL4161934 | — | — | 1 | 9.37 |
| CHEMBL559612 | CP-55940 | — | 1 | 9.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4169198 | — | EC50 | = | 0.03 | nM | 10.52 |
| CHEMBL4177060 | — | EC50 | = | 0.07 | nM | 10.15 |
| CHEMBL4172580 | — | EC50 | = | 0.19 | nM | 9.72 |
| CHEMBL4161934 | — | EC50 | = | 0.43 | nM | 9.37 |
| CHEMBL559612 | CP-55940 | EC50 | = | 0.9 | nM | 9.05 |