Assay Detail
Functional
CHEMBL4145423
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human CXCR7 expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment by chemiluminescence method
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery, Synthesis, Pharmacological Profiling, and Biological Characterization of Brintonamides A-E, Novel Dual Protease and GPCR Modulators from a Marine Cyanobacterium.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 5.18 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4168948 | — | — | 1 | 5.40 |
| CHEMBL4161021 | — | — | 1 | 5.23 |
| CHEMBL4165525 | — | — | 1 | 5.11 |
| CHEMBL4163618 | — | — | 1 | 4.98 |
| CHEMBL4176134 | — | — | 1 | - |
| CHEMBL4174297 | — | — | 1 | - |
| CHEMBL4173913 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4168948 | — | EC50 | = | 3970.0 | nM | 5.40 |
| CHEMBL4161021 | — | EC50 | = | 5920.0 | nM | 5.23 |
| CHEMBL4165525 | — | EC50 | = | 7810.0 | nM | 5.11 |
| CHEMBL4163618 | — | EC50 | = | 10460.0 | nM | 4.98 |
| CHEMBL4176134 | — | EC50 | > | 20000.0 | nM | - |
| CHEMBL4174297 | — | EC50 | > | 20000.0 | nM | - |
| CHEMBL4173913 | — | EC50 | > | 20000.0 | nM | - |