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Assay Detail

CHEMBL4146574

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human GSK3beta by scintillation proximity assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Glycogen synthase kinase-3 beta (CHEMBL262)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Glycogen synthase kinase-3 and its inhibitors: Potential target for various therapeutic conditions.
Saraswati AP, Ali Hussaini SM, Krishna NH, Babu BN, Kamal A.
Eur J Med Chem (2018) 144 : 843 -858
PubMed 29306837 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.30 8.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL182419 1 8.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL182419 IC50 = 5.0 nM 8.30