Assay Detail
Functional
CHEMBL4147039
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Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by SRB assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological evaluation of novel bavachinin analogs as anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.68 | 5.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4175385 | — | — | 1 | 5.11 |
| CHEMBL4169330 | — | — | 1 | 4.94 |
| CHEMBL4177169 | — | — | 1 | 4.60 |
| CHEMBL4159377 | — | — | 1 | 4.53 |
| CHEMBL4173818 | — | — | 1 | 4.52 |
| CHEMBL469444 | BAVACHIN | — | 1 | 4.52 |
| CHEMBL4168912 | — | — | 1 | 4.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4175385 | — | IC50 | = | 7720.0 | nM | 5.11 |
| CHEMBL4169330 | — | IC50 | = | 11430.0 | nM | 4.94 |
| CHEMBL4177169 | — | IC50 | = | 25290.0 | nM | 4.60 |
| CHEMBL4159377 | — | IC50 | = | 29800.0 | nM | 4.53 |
| CHEMBL4173818 | — | IC50 | = | 30500.0 | nM | 4.52 |
| CHEMBL469444 | BAVACHIN | IC50 | = | 30500.0 | nM | 4.52 |
| CHEMBL4168912 | — | IC50 | = | 30700.0 | nM | 4.51 |