Assay Detail
Functional
CHEMBL4147141
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Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MGC-803 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and anti-tumor activity of EF24 analogues as IKKβ inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.43 | 5.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1254461 | — | — | 1 | 5.75 |
| CHEMBL379849 | — | — | 1 | 5.70 |
| CHEMBL471496 | — | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1254461 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL379849 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL471496 | — | IC50 | = | 14200.0 | nM | 4.85 |