Assay Detail
Binding
CHEMBL4147586
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Mycobacterium tuberculosis InhA S94A mutant
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mycobacterium tuberculosis |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Target
Enoyl-[acyl-carrier-protein] reductase [NADH] (CHEMBL1849) ↗| Type | SINGLE PROTEIN |
| Organism | Mycobacterium tuberculosis |
Publication
An overview on crystal structures of InhA protein: Apo-form, in complex with its natural ligands and inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.76 | 6.76 |
| IC50 | 1 | 6.49 | 6.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4174518 | — | — | 2 | 6.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4174518 | — | Ki | = | 172.0 | nM | 6.76 |
| CHEMBL4174518 | — | IC50 | = | 323.0 | nM | 6.49 |