Assay Detail
Binding
CHEMBL4148199
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Trypanosoma cruzi Y epimastigotes PAT assessed as reduction in [3H]--spermidine uptake after 10 mins by liquid scintillation counting method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Trypanosoma cruzi |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Target
Putative amino acid permease/transporter (CHEMBL4295536) ↗| Type | SINGLE PROTEIN |
| Organism | Trypanosoma cruzi |
Publication
Targeting polyamine transport in Trypanosoma cruzi.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.97 | 5.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL558390 | — | — | 1 | 5.06 |
| CHEMBL541629 | — | — | 1 | 4.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL558390 | — | IC50 | = | 8780.0 | nM | 5.06 |
| CHEMBL541629 | — | IC50 | = | 13340.0 | nM | 4.88 |