Assay Detail
Functional
CHEMBL4148489
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiplatelet activity in New Zealand rabbit platelet rich plasma assessed as inhibition of thrombin-induced platelet aggregation preincubated for 1 min followed by thrombin addition measured after 10 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Cell Type | Platelet |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Recent progress in the structural modification and pharmacological activities of ligustrazine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.58 | 9.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2087703 | — | — | 1 | 9.66 |
| CHEMBL539697 | DABIGATRAN ETEXILATE | 4.0 | 1 | 9.49 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2087703 | — | IC50 | = | 0.218 | nM | 9.66 |
| CHEMBL539697 | DABIGATRAN ETEXILATE | IC50 | = | 0.326 | nM | 9.49 |