Assay Detail
Binding
CHEMBL4149388
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HIF-PHD2 (unknown origin) by fluorescence polarization assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Prolyl Hydroxylase Inhibitors: A Breakthrough in the Therapy of Anemia Associated with Chronic Diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.85 | 4.86 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4162752 | DDO-3055 | 1.0 | 1 | 4.86 |
| CHEMBL4173461 | — | — | 1 | 4.86 |
| CHEMBL3646221 | VADADUSTAT | 4.0 | 1 | 4.86 |
| CHEMBL4171364 | — | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4162752 | DDO-3055 | IC50 | = | 13700.0 | nM | 4.86 |
| CHEMBL4173461 | — | IC50 | = | 13700.0 | nM | 4.86 |
| CHEMBL3646221 | VADADUSTAT | IC50 | = | 13700.0 | nM | 4.86 |
| CHEMBL4171364 | — | IC50 | = | 15000.0 | nM | 4.82 |