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Assay Detail

CHEMBL4149484

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibition of human A549 cells after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Intermediate

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

Ajmaline, Oxindole, and Cytotoxic Macroline-Akuammiline Bisindole Alkaloids from Alstonia penangiana.
Yeap JS, Navanesan S, Sim KS, Yong KT, Gurusamy S, Lim SH, Low YY, Kam TS.
J Nat Prod (2018) 81 : 1266 -1277
PubMed 29746134 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.14 5.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4161622 1 5.19
CHEMBL4169538 1 5.08

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4161622 IC50 = 6500.0 nM 5.19
CHEMBL4169538 IC50 = 8300.0 nM 5.08