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Assay Detail

CHEMBL4149570

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiplasmodial activity against Plasmodium falciparum 3D7 infected in human erythrocytes after 72 hrs by SYBR assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Intermediate

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Plasmodial Kinase Inhibitors: License to Cure?
Cabrera DG, Horatscheck A, Wilson CR, Basarab G, Eyermann CJ, Chibale K.
J Med Chem (2018) 61 : 8061 -8077
PubMed 29771541 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.64 6.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1213510 PURFALCAMINE 1 6.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1213510 PURFALCAMINE IC50 = 230.0 nM 6.64