Assay Detail
Binding
CHEMBL4149571
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Plasmodium falciparum recombinant His-tagged CDPK1 expressed in Escherichia coli BL21(DE3) after 1 hr in presence of [gamma33P]ATP by scintillation proximity assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Target
Calcium-dependent protein kinase 1 (CHEMBL1908387) ↗| Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum |
Publication
Plasmodial Kinase Inhibitors: License to Cure?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.01 | 7.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4175786 | — | — | 1 | 7.43 |
| CHEMBL4165173 | — | — | 1 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4175786 | — | Ki | = | 37.0 | nM | 7.43 |
| CHEMBL4165173 | — | Ki | = | 262.0 | nM | 6.58 |