Assay Detail
Functional
CHEMBL4149577
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Antiplasmodial activity against Plasmodium falciparum NF54
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Plasmodial Kinase Inhibitors: License to Cure?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.02 | 8.52 |
| EC50 | 2 | 5.40 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL307261 | ARTENIMOL | 3.0 | 1 | 8.52 |
| CHEMBL2030554 | — | — | 1 | 5.70 |
| CHEMBL98350 | LY-294002 | -1.0 | 1 | 5.52 |
| CHEMBL2078876 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL307261 | ARTENIMOL | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL2030554 | — | EC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL98350 | LY-294002 | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL2078876 | — | EC50 | = | 8000.0 | nM | 5.10 |