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Assay Detail

CHEMBL4149587

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Plasmodium falciparum MRK
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Plasmodium falciparum
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Protein kinase Pfmrk (CHEMBL4090)
Type SINGLE PROTEIN
Organism Plasmodium falciparum

Publication

Plasmodial Kinase Inhibitors: License to Cure?
Cabrera DG, Horatscheck A, Wilson CR, Basarab G, Eyermann CJ, Chibale K.
J Med Chem (2018) 61 : 8061 -8077
PubMed 29771541 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.75 4.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL97218 1 4.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL97218 IC50 = 18000.0 nM 4.75