Assay Detail
Functional
CHEMBL4149607
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human HepG2 cells after 6 days by MTT assay
10
Total Activities
10
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Cytotoxic and Antibacterial Eremophilane Sesquiterpenes from the Marine-Derived Fungus Cochliobolus lunatus SCSIO41401.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.44 | 5.85 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4160097 | — | — | 1 | 5.85 |
| CHEMBL289277 | EMODIN | — | 1 | 5.77 |
| CHEMBL4171739 | — | — | 1 | 5.23 |
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 4.92 |
| CHEMBL4170405 | — | — | 1 | - |
| CHEMBL4163855 | — | — | 1 | - |
| CHEMBL4160948 | — | — | 1 | - |
| CHEMBL4168887 | — | — | 1 | - |
| CHEMBL4164350 | — | — | 1 | - |
| CHEMBL509319 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4160097 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL289277 | EMODIN | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL4171739 | — | IC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL185 | FLUOROURACIL | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL4170405 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL4163855 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL4160948 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL4168887 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL4164350 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL509319 | — | Activity | - | — | - |