Assay Detail
Binding
CHEMBL4150530
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CDK19 (M1 to N360 residues) expressed in bacterial expression system by KINOMEscan assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of Highly Potent and Selective Steroidal Inhibitors and Degraders of CDK8.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.10 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4167193 | — | — | 1 | 8.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4167193 | — | IC50 | = | 8.0 | nM | 8.10 |