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Assay Detail

CHEMBL4151734

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Inhibition of mammalian protein synthesis in rabbit reticulocyte lysate system incubated for 1 hr by mammalian cell-free transcription-translation assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Oryctolagus cuniculus
Subcellular Lysate
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Total Synthesis and Structure-Activity Relationships Study of Odilorhabdins, a New Class of Peptides Showing Potent Antibacterial Activity.
Sarciaux M, Pantel L, Midrier C, Serri M, Gerber C, Marcia de Figueiredo R, Campagne JM, Villain-Guillot P, Gualtieri M, Racine E.
J Med Chem (2018) 61 : 7814 -7826
PubMed 30086230 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.99 4.99

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4163760 1 4.99
CHEMBL4174689 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4163760 IC50 = 10300.0 nM 4.99
CHEMBL4174689 IC50 = 167700.0 nM -