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Assay Detail

CHEMBL4152407

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced superoxide anion generation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Neutrophil
Confidence 1 — Organism
Curated By Intermediate

Target

Neutrophil (CHEMBL5314326)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent acquisitions on oxyprenylated secondary metabolites as anti-inflammatory agents.
Fiorito S, Epifano F, Taddeo VA, Genovese S.
Eur J Med Chem (2018) 153 : 116 -122
PubMed 28844340 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.77 5.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL453805 PENTOSALEN -1.0 1 5.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL453805 PENTOSALEN IC50 = 1700.0 nM 5.77