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Assay Detail

CHEMBL4152546

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Functional
Inhibition of LPS-stimulated mPGES1 expression in mouse J774 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type J774
Confidence 1 — Organism
Curated By Intermediate

Target

J774 (CHEMBL614123)
Type CELL-LINE
Organism Mus musculus

Publication

Plant-derived mPGES-1 inhibitors or suppressors: A new emerging trend in the search for small molecules to combat inflammation.
Khan H, Rengasamy KRR, Pervaiz A, Nabavi SM, Atanasov AG, Kamal MA.
Eur J Med Chem (2018) 153 : 2 -28
PubMed 29329790 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.85 4.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3098864 1 4.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3098864 IC50 = 14000.0 nM 4.85