Assay Detail
Binding
CHEMBL4153654
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of tetrahymena GCN5 (48 to 210 residues)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Tetrahymena |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Target
Histone acetyltransferase GCN5 (CHEMBL4295593) ↗| Type | SINGLE PROTEIN |
| Organism | Tetrahymena thermophila (strain SB210) |
Publication
Discovery of 1,8-acridinedione derivatives as novel GCN5 inhibitors via high throughput screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.30 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4161210 | — | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4161210 | — | IC50 | = | 500.0 | nM | 6.30 |