Assay Detail
Functional
CHEMBL4153859
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Cytotoxicity against human HT-29 cells after 96 hrs by SRB assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Targeting mitochondria: Esters of rhodamine B with triterpenoids are mitocanic triggers of apoptosis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 12 | 5.97 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4160690 | — | — | 1 | 7.22 |
| CHEMBL4160108 | — | — | 1 | 6.82 |
| CHEMBL4164094 | — | — | 1 | 6.35 |
| CHEMBL4160966 | — | — | 1 | 6.34 |
| CHEMBL4165192 | — | — | 1 | 6.28 |
| CHEMBL4174175 | — | — | 1 | 6.21 |
| CHEMBL4176714 | — | — | 1 | 5.85 |
| CHEMBL4163693 | — | — | 1 | 5.73 |
| CHEMBL4170752 | — | — | 1 | 5.56 |
| CHEMBL4171970 | — | — | 1 | 5.27 |
| CHEMBL4162296 | — | — | 1 | 5.05 |
| CHEMBL4163475 | — | — | 1 | 4.94 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4160690 | — | EC50 | = | 60.0 | nM | 7.22 |
| CHEMBL4160108 | — | EC50 | = | 150.0 | nM | 6.82 |
| CHEMBL4164094 | — | EC50 | = | 450.0 | nM | 6.35 |
| CHEMBL4160966 | — | EC50 | = | 460.0 | nM | 6.34 |
| CHEMBL4165192 | — | EC50 | = | 530.0 | nM | 6.28 |
| CHEMBL4174175 | — | EC50 | = | 610.0 | nM | 6.21 |
| CHEMBL4176714 | — | EC50 | = | 1420.0 | nM | 5.85 |
| CHEMBL4163693 | — | EC50 | = | 1850.0 | nM | 5.73 |
| CHEMBL4170752 | — | EC50 | = | 2750.0 | nM | 5.56 |
| CHEMBL4171970 | — | EC50 | = | 5330.0 | nM | 5.27 |
| CHEMBL4162296 | — | EC50 | = | 8900.0 | nM | 5.05 |
| CHEMBL4163475 | — | EC50 | = | 11410.0 | nM | 4.94 |