Assay Detail
Functional
CHEMBL4153860
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Cytotoxicity against human MCF7 cells after 96 hrs by SRB assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Targeting mitochondria: Esters of rhodamine B with triterpenoids are mitocanic triggers of apoptosis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 12 | 5.99 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4160690 | — | — | 1 | 7.40 |
| CHEMBL4160108 | — | — | 1 | 6.75 |
| CHEMBL4164094 | — | — | 1 | 6.52 |
| CHEMBL4160966 | — | — | 1 | 6.44 |
| CHEMBL4165192 | — | — | 1 | 6.33 |
| CHEMBL4174175 | — | — | 1 | 6.09 |
| CHEMBL4176714 | — | — | 1 | 5.83 |
| CHEMBL4163693 | — | — | 1 | 5.74 |
| CHEMBL4170752 | — | — | 1 | 5.64 |
| CHEMBL4171970 | — | — | 1 | 5.30 |
| CHEMBL4162296 | — | — | 1 | 5.03 |
| CHEMBL4163475 | — | — | 1 | 4.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4160690 | — | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL4160108 | — | EC50 | = | 180.0 | nM | 6.75 |
| CHEMBL4164094 | — | EC50 | = | 300.0 | nM | 6.52 |
| CHEMBL4160966 | — | EC50 | = | 360.0 | nM | 6.44 |
| CHEMBL4165192 | — | EC50 | = | 470.0 | nM | 6.33 |
| CHEMBL4174175 | — | EC50 | = | 810.0 | nM | 6.09 |
| CHEMBL4176714 | — | EC50 | = | 1470.0 | nM | 5.83 |
| CHEMBL4163693 | — | EC50 | = | 1830.0 | nM | 5.74 |
| CHEMBL4170752 | — | EC50 | = | 2310.0 | nM | 5.64 |
| CHEMBL4171970 | — | EC50 | = | 5050.0 | nM | 5.30 |
| CHEMBL4162296 | — | EC50 | = | 9400.0 | nM | 5.03 |
| CHEMBL4163475 | — | EC50 | = | 13750.0 | nM | 4.86 |