Assay Detail
Functional
CHEMBL4154332
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at mouse GPR40
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis and structure-activity relationship studies of GPR40 agonists containing amide linker.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.51 | 7.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4167323 | — | — | 1 | 7.64 |
| CHEMBL4172828 | — | — | 1 | 7.51 |
| CHEMBL4166892 | — | — | 1 | 7.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4167323 | — | EC50 | = | 23.0 | nM | 7.64 |
| CHEMBL4172828 | — | EC50 | = | 31.0 | nM | 7.51 |
| CHEMBL4166892 | — | EC50 | = | 42.0 | nM | 7.38 |