Assay Detail
Functional
CHEMBL4155551
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against promastigote stage of Leishmania donovani LdBOB over-expressing NTR2 assessed as inhibition of parasite growth after 72 hrs by resazurin assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania donovani |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel 8-nitroquinolin-2(1H)-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.34 | 5.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4170207 | — | — | 1 | 5.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4170207 | — | IC50 | = | 4600.0 | nM | 5.34 |