Assay Detail
ADMET
CHEMBL4155617
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Cytotoxicity against human LO2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | L02 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological activities of dithiocarbamates containing 2(5H)-furanone-piperazine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.24 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4170859 | — | — | 1 | 6.96 |
| CHEMBL803 | CYTARABINE | 4.0 | 1 | 6.77 |
| CHEMBL90555 | VINCRISTINE | 4.0 | 1 | 6.70 |
| CHEMBL4173473 | — | — | 1 | 6.43 |
| CHEMBL4165545 | — | — | 1 | 4.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4170859 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL803 | CYTARABINE | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL90555 | VINCRISTINE | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL4173473 | — | IC50 | = | 370.0 | nM | 6.43 |
| CHEMBL4165545 | — | IC50 | = | 45760.0 | nM | 4.34 |