Assay Detail
Binding
CHEMBL4157963
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]SR141716A from membrane bound human CB1 receptor after 1 hr by beta scintillation counting method
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis of oxidative metabolites of CRA13 and their analogs: Identification of CRA13 active metabolites and analogs thereof with selective CB2R affinity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.85 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL244403 | — | — | 1 | 5.80 |
| CHEMBL4169849 | — | — | 1 | 4.85 |
| CHEMBL4161845 | — | — | 1 | 4.75 |
| CHEMBL4167940 | — | — | 1 | 4.00 |
| CHEMBL4176969 | — | — | 1 | - |
| CHEMBL4166345 | — | — | 1 | - |
| CHEMBL4159535 | — | — | 1 | - |
| CHEMBL4161451 | — | — | 1 | - |
| CHEMBL4176556 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL244403 | — | IC50 | = | 1580.0 | nM | 5.80 |
| CHEMBL4169849 | — | IC50 | = | 14130.0 | nM | 4.85 |
| CHEMBL4161845 | — | IC50 | = | 17920.0 | nM | 4.75 |
| CHEMBL4167940 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL4176969 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4166345 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4159535 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4161451 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4176556 | — | IC50 | > | 100000.0 | nM | - |