Assay Detail
ADMET
CHEMBL4158855
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant HSP90alpha expressed in Escherichia coli by fluorescence polarization assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a Potent Grp94 Selective Inhibitor with Anti-Inflammatory Efficacy in a Mouse Model of Ulcerative Colitis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.88 | 4.88 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3426787 | — | — | 1 | 4.88 |
| CHEMBL4166329 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3426787 | — | IC50 | = | 13100.0 | nM | 4.88 |
| CHEMBL4166329 | — | IC50 | > | 250000.0 | nM | - |